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REFERENCES CITING USE OF PROFECT REAGENTS
- Pereira, M., Tourlomousis, P., Wright, J., P Monie, T., & Bryant, C. E. (2016). CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. Nature communications, 7, 12874. https://doi.org/10.1038/ncomms12874
- Miao EA, Alouche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI amd Aderem A(2006) Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1 via Ipaf. Nature Immunology, 7 , 569-575
- Edward A. Miao, Dat P. Mao, Natalya Yudkovsky, Richard Bonneau, Cynthia G. Lorang, Sarah E. Warren, Irina A. Leaf, and Alan Aderem. (2010) Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome PNAS, Feb 2010; 107: 3076 - 3080.
- Qing Yao, Jixin Cui, Yongqun Zhu, Guolun Wang, Liyan Hu, Chengzu Long, Ran Cao, Xinqi Liu, Niu Huang, She Chen, Liping Liu, and Feng Shao (2009) A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle PNAS, Mar 2009; 106: 3716 - 3721.
- Nandan D, Yi T, Lopez M, Lai C, Reiner NE. (2002) Leishmania EF-1alpha activates the Src homology 2 domain containing tyrosine phosphatase SHP-1 leading to macrophage deactivation. J Biol Chem. 2002 Dec 20;277(51):50190-7.
- Tanaka H, I Matsumura I, Itoh K, Hatsuyamaa A, Shikamura M, Satoh Y, Heike T, Nakahata T, Kanakura Y. (2006). HOX Decoy Peptide Enhances the Ex Vivo Expansion of Human Umbilical Cord 9. Blood CD34+ Hematopoietic Stem Cells/Hematopoietic Progenitor Cells. Stem Cells Vol. 24 No. 11 November 2006, pp. 2592-2602 doi:10.1634/stemcells.2005
- Sendide K, Deghmane A’E, Pechkovsky D, Av-Gay Y,(2005) Mycobacterium bovis BCG Attenuates Surface Expression of Mature Class II Molecules through IL-10-Dependent Inhibition of Cathepsin S. J Immunol. 2005 Oct 15;175(8):5324-32. doi: 10.4049/jimmunol.175.8.5324.
- Sato, Ken-ichi, Nagao, Tomomi, Iwasaki, Tetsushi, Nishihira, Yusuke & Fukami, Yasuo (2003) Src- dependent phosphorylation of the EGF receptor Tyr-845 mediates Stat-p21waf1 pathway in A431 cells. Genes to Cells 8 (12), 995-1003.
- Heidi A. Erickson1, Michelle D. Jund1 and Christopher A. Pennell1,2 Cytotoxicity of human RNase-based immunotoxins requires cytosolic access and resistance to ribonuclease inhibition Protein Engineering Design and Selection 2006 19(1):37-45;
- Takami T, Terai S, Yokoyama Y, Tanimoto H, Tajima K, Uchida K, Yamasaki T, Sakaida I, Nishina H, Thorgeirsson SS, Okita K. (2005) Human homologue of maid is a useful marker protein in hepatocarcinogenesis. Gastroenterology. 2005 May;128(5):1369-80. doi: 10.1053/j.gastro.2005.03.014.
- Xavier A, Al-Zeer MA, Meyer TF, Daumke O. hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation through Sequential GTP Hydrolysis. Cell Rep. 2020 May 19;31(7):107667. doi:
10.1016/j.celrep.2020.107667. PMID: 32433976.
- Vural, A., Nabar, N. R., Hwang, I. Y., Sohn, S., Park, C., Karlsson, M., Blumer, J. B., & Kehrl, J. H. (2019). Gαi2 Signaling Regulates Inflammasome Priming and Cytokine Production by Biasing Macrophage Phenotype Determination. Journal of immunology, 202(5), 1510–1520.
https://doi.org/10.4049/jimmunol.1801145
- Gong, YN., Wang, X., Wang, J. et al. Chemical probing reveals insights into the signaling mechanism of inflammasome activation. Cell Res 20, 1289–1305 (2010). https://doi.org/10.1038/cr.2010.135
- Zhao C, Gillette DD, Li X, Zhang Z, Wen H. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J Biol Chem. 2014 Jun 13;289(24):17020-9. doi:
10.1074/jbc.M114.563114
- Pu, Q., Gan, C., Li, R., Li, Y., Tan, S., Li, X., Wei, Y., Lan, L., Deng, X., Liang, H., Ma, F., & Wu, M. (2017). Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis. Journal of immunology, 198(8), 3205–3213. https://doi.org/10.4049/jimmunol.1601196
- Lightfield, K. L., Persson, J., Trinidad, N. J., Brubaker, S. W., Kofoed, E. M., Sauer, J. D., Dunipace, E. A., Warren, S. E., Miao, E. A., & Vance, R. E. (2011). Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infection and immunity, 79(4), 1606–1614. https://doi.org/10.1128/IAI.01187-10
- Hafid Soualhine, Ala-Eddine Deghmane, Jim Sun, Karen Mak, Amina Talal, Yossef Av-Gay, and Zakaria Hmama (2007) Mycobacterium bovis Bacillus Calmette-Guérin Secreting Active Cathepsin S Stimulates Expression of Mature MHC Class II Molecules and Antigen Presentation in Human Macrophages J. Immunol., Oct. 2007; 5137-5145
- M. Suzuki, H. Mimuro, K. Kiga, M. Fukumatsu, N. Ishijima, H. Morikawa, S. Nagai, S. Koyasu, R. Gilman, D. Kersulyte (2009) Helicobacter pylori CagA Phosphorylation-Independent Function in Epithelial Proliferation and Inflammation Cell Host & Microbe Volume 5, Issue 1, 22 January 2009, Pages 23-34
- Nandan D, Yi T, Lopez M, Lai C, Reiner NE. (2002) Leishmania EF-1alpha activates the Src homology 2 domain containing tyrosine phosphatase SHP-1 leading to macrophage deactivation Biol Chem. 2002 Dec 20;277(51):50190-7. Murine Macrophage cells
- Nandan D and Reiner NE (2005) , Leishmania donovani engages in regulatory interference by targeting macrophage protein tyrosine phosphatase SHP-1 Clinical Immunology 114: (3) Pages 266-277.
- Sarah E. Warren, Dat P. Mao, April E. Rodriguez, Edward A. Miao, and Alan Aderem (2008) Multiple Nod- Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection. (2008) Multiple Nod-Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection. J. Immunol., Jun 2008; 180: 7558 -
7564.
- Natalie N. Whitfield, Brenda G. Byrne, and Michele S. Swanson* Mouse Macrophages are Permissive to Motile Legionella Species that Fail to Trigger PyroptosisInfect. Immun. doi:10.1128/IAI.00070-09
- Natalie Nicole Whitfield (2009) Flagellin is critical for Legionella motility and macrophage recognition, PhD dissertation, Dept of Cellular and Molecular Biology, University of Michigan, 2009.
- Natalie N. Whitfield, Brenda G. Byrne, and Michele S. Swanson (2010) Mouse Macrophages Are Permissive to Motile Legionella Species That Fail to Trigger Pyroptosis Infect. Immun. 78: 423 - 432.
- López-Yglesias AH, Lu CC, Zhao X, Chou T, VandenBos T, Strong RK, Smith KD. FliC's Hypervariable D3 Domain Is Required for Robust Anti-Flagellin Primary Antibody Responses. Immunohorizons. (2019) Sep 5;3(9):422-432. doi: 10.4049/immunohorizons.1800061. PMID: 31488506.
- Jun HK, Jung YJ, Choi BK. Inflammasome activators induce fibronectin expression and release in macrophages. Cell Microbiol. (2017) May;19(5). doi: 10.1111/cmi.12695. Epub 2017 Jan 5. PMID: 27870323.
- Shi, C. S., & Kehrl, J. H. (2016). Cytochrome c Negatively Regulates NLRP3 Inflammasomes. PloS one, 11(12), e0167636. https://doi.org/10.1371/journal.pone.0167636
- López-Yglesias, A. H., Zhao, X., Quarles, E. K., Lai, M. A., VandenBos, T., Strong, R. K., & Smith, K. D. (2014). Flagellin induces antibody responses through a TLR5- and inflammasome-independent
pathway. Journal of immunology, 192(4), 1587–1596. https://doi.org/10.4049/jimmunol.1301893
References on proteojuice (Profect P2 is sold by Novagen under the name of proteojuice)
- Cytotoxicity of human RNase-based immunotoxins requires cytosolic access and resistance to ribonuclease inhibition. Heidi A. Erickson, Michelle D. Jund, Christopher A. Pennell Protein Eng. Des. Sel., Jan 2006; 19: 37 - 45.
- NOD2/CARD15 Mediates Induction of the Antimicrobial Peptide Human Beta-defensin-2. Eske Voss, Jan Wehkamp, Kai Wehkamp, Eduard F. Stange, Jens M. Schröder, and Jürgen Harder. J. Biol. Chem., Jan 2006; 281: 2005 - 2011.
- Agnieszka Gizak 1 *, Ewa Maciaszczyk-Dziubinska 2, Magdalena Jurowicz 1, Dariusz Rakus 1 (2009) Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence. Proteins: Structure, Function, and Bioinformatics
Volume 77 Issue 2, Pages 262 - 267 (protein delivery into HL1 cardiac myocytes)
- Recombinase mediated cassette exchange into genomic targets using an adenovirus vector (2010) David A. Sorrell, Claire J. Robinson, Jo-Ann Smith, and Andreas F. Kolb
Nucleic Acids Res., Apr 2010; 10.1093/nar/gkq192. (CRE recominase delivered into HC11 cells)
- Aitziber L. Cortajarena†, Fang Yi† and Lynne Regan†‡* (2008) Designed TPR Modules as Novel Anticancer Agents. ACS Chem. Biol., 2008, 3 (3), pp 161–166
(TPR modules delivered into BT474 cells) - human breast tumor cell line
- Tian-Tian Wang, Basel Dabbas, David Laperriere, Ari J. Bitton, Hafid Soualhine, Luz E. Tavera-Mendoza, Serge Dionne, Marc J. Servant, Alain Bitton, Ernest G. Seidman, Sylvie Mader, Marcel A. Behr, and John H. White (2010) Direct and Indirect Induction by 1,25-Dihydroxyvitamin D3 of the NOD2/CARD15-Defensin ß2 Innate Immune Pathway Defective in Crohn Disease
J. Biol. Chem., Jan 2010; 285: 2227 - 2231.
References citing use of Targefect reagents for gene delivery
- Downes M, Ordentlich P, Kao H-Y, Jacqueline GA Alvarez and Evans RM. (2000) Identification of a nuclear domain with deacetylase activity. Proc. Natl.. Acad. Sci., USA, 97 (19) : 10330-10335
HEK-293, CV-1
- Kao H-Y, Downes M, Ordentlich P and Evans RM (2000) Isolation of a novel histone deacetylase reveals that class 1 and class II deacetylases promote SMRT-mediated repressio. Genes and Development. 14: 55-66
HEK-293, CV-1
- Magnana MM, Koo S-H, Towle HC and Osborne TF (2000) Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase. J. Biol. Chem. 275(7): 4726-4733
Hepatocyte (rat)
- Koo SH and Towle HC (2000) Glucose regulation of mouse S-14 gene expression in hepatocytes- involvement of a novel transcription factor complex. J. Biol. Chem 275(7): 5200-5207
Hepatocyte (rat)
- Grammatikakis N, Lin JH, Grammatikakis A, Tsichlis PN and Cochran BH (1999) . p 50 acting in concert with Hsp 90 is required for Raf-1 function. Mol. And Cell. Biol. 19(3): 1661-1672.
HEK-293
- Johnson SAS, Mandavia N, Wang HD, and Johnson DL (2000) Transcriptional regulation of the TATA-binding protein by Ras cellular signaling. Mol. Cell. Biol. 20 (14): 5000-9.
Hepatocyte (rat)
- Koo SH, Dutcher AK and Towle HCl (2001). Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzymes in liver. J. Biol. Chem. (275(10): 1074
Hepatocyte (rat)
- Elizabeth N. Kaytor, Juan Li Zhu, Ching-I Pao, and Lawrence S. Phillips (2001). Insulin-responsive nuclear proteins facilitate Sp1 interactions with the IGF-I gene J. Biol. Chem. published July 16, 2001 as 10.1074/jbc.M104035200 HepG2 cells
- Ben-Quan Shen, David Y. Lee, Hans-Peter Gerber, Bruce A. Keyt, Napoleone Ferrara, and Thomas F. Zioncheck (1998) Homologous Up-regulation of KDR/Flk-1 Receptor Expression by Vascular Endothelial Growth Factor in Vitro J. Biol. Chem. 273: 29979-29985.
HUVECs (Human umbilical vein endothelial cells)
- Brennon L. O‘Callaghan, Seung-Hoi Koo, Yue Wu, Hedley C. Freake, and Howard C. Towle (2001)Glucose Regulation of the Acetyl-CoA Carboxylase Promoter PI in Rat Hepatocytes J. Biol. Chem. 276: 16033-16039
Hepatocyte (rat)
- Yanhong Shi, Michael Downes, Wen Xie, Hung-Ying Kao, Peter Ordentlich, Chih-Cheng Tsai, Michelle Hon, and Ronald M. Evans (2001) Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. Genes and Development Vol. 15, No. 9, pp. 1140-1151,
HEK-293
- Nanping Wang, Lynne Verna, Hai-ling Liao, Alex Ballard, Yi Zhu, and Michael B. Stemerman . Adenovirus-Mediated Overexpression of Dominant-Negative Mutant of c-Jun Prevents Intercellular Adhesion Molecule-1 Induction by LDL: A Critical Role for Activator Protein-1 in Endothelial Activation Arterioscler. Thromb. Vasc. Biol. 21: 1414-1420
HUVECs (Human umbilical vein endothelial cells)
- Zhu, Hailing Liao, Nanping Wang, Kuo-Sheng Ma, Lynne K. Verna, John Y.-J. Shyy, Shu Chien, and Michael B. Stemerman LDL-Activated p38 in Endothelial Cells Is Mediated by Ras. Arterioscler. Thromb. Vasc. Biol. 21: 1159-1164
HUVECs (Human umbilical vein endothelial cells)
- Nanping Wang, Lynne Verna, Neng-Guin Chen, Jasmine Chen, Hongling Li, Barry Marc Forman, and Michael B. Stemerman (2002)Constitutive Activation of Peroxisome Proliferator-activated Receptor-Suppresses Pro-inflammatory Adhesion Molecules in Human Vascular Endothelial Cells. J. Biol. Chem, 277: 34176-34181.
HUVECs (Human umbilical vein endothelial cells)
- Hailing Liao, Thomas Langmann, Gerd Schmitz, and Yi Zhu (2002)Native LDL Upregulation of ATP-Binding Cassette Transporter-1 in Human Vascular Endothelial Cells Arterioscler. Thromb. Vasc. Biol. 22: 127 - 132. HUVECs (Human umbilical vein endothelial cells)
- Hongwei Li, Sungmin Park, Britta Kilburn, Mary Anne Jelinek, Agnes Henschen-Edman, Dana W. Aswad, Michael R. Stallcup, and Ite A. Laird-Offringa (2002) Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1 J. Biol. Chem., 277: 44623 - 44630.
- Stephen S. Koh, Hongwei Li, Young-Ho Lee, Randall B. Widelitz, Cheng-Ming Chuong, and Michael R. Stallcup (2002) Synergistic Coactivator Function by Coactivator-associated Arginine Methyltransferase (CARM) 1 and Beta-Catenin with Two Different Classes of DNA-binding Transcriptional Activators J. Biol. Chem. 277: 26031-26035.
Cos-7 cells
- Keyvan Mahboubi and Jordan S. Pober Activation of Signal Transducer and Activator of Transcription 1 (STAT1) Is Not Sufficient for the Induction of STAT1-dependent Genes in Endothelial Cells. COMPARISON OF INTERFERON-AND ONCOSTATIN M (2002) J. Biol. Chem. 277: 8012-8021.
HepG2 cells
- Young-Ho Lee, Stephen S. Koh, Xing Zhang, Xiaodong Cheng, and Michael R. Stallcup (2002) Synergy among Nuclear Receptor Coactivators: Selective Requirement for Protein Methyltransferase and Acetyltransferase Activities Mol. Cell. Biol., 22: 3621 - 3632.
CV-1 cells
- Hella Wobser, Heiko Düßmann, Donat Kögel, Haiyan Wang, Claus Reimertz, Claes B. Wollheim, Maria M. Byrne, and Jochen H. M. Prehn (2002) Dominant-negative Suppression of HNF-1Results in Mitochondrial Dysfunction, INS-1 Cell Apoptosis, and Increased Sensitivity to Ceramide-, but Not to High Glucose-induced Cell Death J. Biol. Chem. 277: 6413-6421.
INS-1 cells
- Xiaoyong Yang, Fengxue Zhang, and Jeffrey E. Kudlow (2002) Recruitment of O-GlcNAc Transferase to Promoters by Corepressor mSin3A: Coupling Protein O-GlcNAcylation to Transcriptional Repression. Cell 2002 110: 69-80.
Cos-7 cells
- Marc Tini, Arndt Benecke, Soo-Joong Um, Joseph Torchia, Ronald M. Evans, and Pierre Chambon (2002) Association of CBP/p300 Acetylase and Thymine DNA Glycosylase Links DNA Repair and Transcription. Molecular Cell 9: 265- 277.
Cos-1 cells, MCF-7
- Hongyun She, Shigang Xiong, Min Lin, Ebrahim Zandi, Cecilia Giulivi, and Hidekazu Tsukamoto. (2002) Iron activates NF-B in Kupffer cells Am J Physiol Gastrointest Liver Physiol, 283: 719 - 726.
Kupffer cells
- Etsuro Hatano and David A. Brenner. (2001) Akt protects mouse hepatocytes from TNF-- and Fas-mediated apoptosis through NK-B activation Am J Physiol Gastrointest Liver Physiol, 281: 1357 - 1368.
Hepatocytes (rat)
- David P. Hughes, Marie B. Marron, and Nicholas P.J. Brindle (2003) The Antiinflammatory Endothelial Tyrosine Kinase Tie2 Interacts With a Novel Nuclear Factor-B Inhibitor ABIN-2. Circ. Res., 92: 630 - 636.
CHO cells, HUVECs (Human umbilical vein endothelial cells)
- C. Marc Luetjens, Donat Kögel, Claus Reimertz, Heiko Düßmann, Andrea Renz, Klaus Schulze-Osthoff, Anna-Liisa Nieminen, Monika Poppe, and Jochen H. M. Prehn (2001) Multiple Kinetics of Mitochondrial Cytochrome c Release in Drug-Induced Apoptosis. Mol. Pharmacol., 60: 1008 - 1019
MCF-7 cells
- Monika Poppe, Claus Reimertz, Heiko Düßmann, Aaron J. Krohn, C. Marc Luetjens, Doris Böckelmann, Anna-Liisa Nieminen, Donat Kögel, and Jochen H. M. Prehn (2001) Dissipation of Potassium and Proton Gradients Inhibits Mitochondrial Hyperpolarization and Cytochrome c Release during Neural Apoptosis. J. Neurosci., 21: 4551 - 4563.
Human medulloblastoma D283, MCF-7
- Li H, Park S, Kilburn B, Jelinek MA, Henschen-Edman A, Aswad DW, Stallcup MR, Laird-Offringa IA. (2002) Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase. J Biol Chem. 277(47):44623-30.
Cos-7
- Koh SS, Li H, Lee YH, Widelitz RB, Chuong CM, Stallcup MR. (2002) Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators.J Biol Chem. 277(29):26031-5.
CV-1, Cos-7
- Robert F. Schwabe, Cynthia A. Bradham, Tetsuya Uehara, Etsuro Hatano , Brydon L. Bennett , Robert Schoonhoven , David A. Brenner (2003) c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. Hepatology . Volume 37 • Number 4 • p824 to p832
Hepatocytes (rat)
- Takako Kitani, Sachiko Okuno, Masayuki Takeuchi, and Hitoshi Fujisawa (2003) Subcellular distributions of rat CaM kinase phosphatase N and other members of the CaM kinase regulatory system J. Neurochem., 86: 77 - 85.
PC-12 cells
- Quang-Kim Tran, D. J. Black, and Anthony Persechini (2003) Intracellular Coupling via Limiting Calmodulin J. Biol. Chem., 278: 24247 - 24250.
HUVECs (Human umbilical vein endothelial cells
- Amir Tadros, David P Hughes, Benjamin J Dunmore, and Nicholas P J Brindle (2003) ABIN-2 protects endothelial cells from death and has a role in the anti-apoptotic effect of angiopoietin-1. Blood, 10.1182/blood-2003-05-1602.
HUVECs (Human umbilical vein endothelial cells)
- Vadim Iourgenko, Wenjun Zhang, Craig Mickanin, Ira Daly, Can Jiang, Jonathan M. Hexham, et al (2003) Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. PNAS, 10.1073/pnas.1932773100.
Hela cells
- Radu V. Stan.(2003) Multiple PV1 Dimers Reside in the Same Stomatal or Fenestral Diaphragm Am J Physiol Heart Circ Physiol, 10.1152/ajpheart.00909.2003
HUVECs (Human umbilical vein endothelial cells), HEK-293, Cos-7
- Guifu Wu, Arjuna P. Mannam, Jiaping Wu, Simona Kirbis, Jue-Lon Shie, Christopher Chen, Roger J. Laham, Frank W. Sellke, and Jian Li (2003) Hypoxia induces myocyte-dependent COX-2 regulation in endothelial cells: role of VEGF. Am J Physiol Heart Circ Physiol, 285: 2420
HUVECs , HMVECs (microvascular endothelial cells)
- Jeong Hoon Kim, Hongwei Li, and Michael R. Stallcup (2003) CoCoA, a Nuclear Receptor Coactivator which Acts through an N-Terminal Activation Domain of p160 Coactivators Molecular Cell 12: 1537-1549
CV-1 cells
- Hung-Ying Kao, André Verdel, Chih-Cheng Tsai, Cynthia Simon, Henry Juguilon, and Saadi Khochbin (2001) Mechanism for Nucleocytoplasmic Shuttling of Histone Deacetylase . J. Biol. Chem., Dec 2001; 276: 47496 - 47507.
HUVECs (Human umbilical vein endothelial cells)
- Yanhong Shi, Michelle Hon, and Ronald M. Evans (2002) The peroxisome proliferator-activated receptor , an integrator of transcriptional repression and nuclear receptor signaling. PNAS, 99: 2613 - 2618.
HEK-293
- Hung-Ying Kao, Chih-Hao Lee, Andrei Komarov, Chris C. Han, and Ronald M. Evans (2001) Isolation and Characterization of Mammalian HDAC10, a Novel Histone Deacetylase. J. Biol. Chem., Dec 2001; 277: 187 - 193.
HEK-293
- Chin K. Sung, Hongyun She, Shigang Xiong, and Hidekazu Tsukamoto Tumor necrosis factor-inhibits peroxisome proliferator-activated receptor activity at a posttranslational level in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol, May 2004; 286: 722 – 729 Liver stellate cells
- Increased transcriptional activity of the CYP3A4*1B promoter variant (2003) B. Amirimani, B. Ning, A.C. Deitz, B.L. Weber, F.F. Kadlubar, T.R. Rebbeck Environmental and Molecular Mutagenesis. Volume 42, Issue 4, .Pages 299-305 Hepatocytes (Human)
- Bo Lu, Yi Mu, Carolyn Cao, Fenghua Zeng, Sylke Schneider, Jiahui Tan, Jim Price, Jun Chen, Michael Freeman, and Dennis E. Hallahan (2004) Survivin As a Therapeutic Target for Radiation Sensitization in Lung Cancer Cancer Res., 64: 2840 - 2845. HUVECs (Human umbilical vein endothelial cells)
- Angela K. Stoeckman, Lin Ma, and Howard C. Towle (2004) Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes. J. Biol. Chem., 279: 15662 - 15669.
Hepatocyte (rat)
- Jiaping Wu, Cherie Parungo, Guifu Wu, Peter M. Kang, Roger J. Laham, Frank W. Sellke, Michael Simons, and Jian Li (2004) PR39 Inhibits Apoptosis in Hypoxic Endothelial Cells: Role of Inhibitor Apoptosis Protein-2. Circulation, ; 109: 1660 - 1667.
HUVECs (Human umbilical vein endothelial cells)
- Saswati Hazra, Shigang Xiong, Jiaohong Wang, Richard A. Rippe, V. Krishna, K. Chatterjee, and Hidekazu Tsukamoto (2004) Peroxisome Proliferator-activated Receptor Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells J. Biol. Chem., 279: 11392 - 11401.
Hepatic stellate cells
- Suksaweang, S., Lin C-M., Jiang, T-X., Hughes, M.W., Widelitz, R.B., and Chuong, C-M. 2004. Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation. Dev Biol. 266: 109-122.
Liver stem cells
- Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky, Marc Montminy.(2004) PGC-1 promotes insulin resistance in liver through PPAR--dependent induction of TRB-3 . Nature Medicine10, 530 - 534 (01 May 2004) Letters
Hepatocyte (rat)
- Nary Veal, Chih-Lin Hsieh, Shigang Xiong, Jose M. Mato, Shelly Lu, and Hidekazu Tsukamoto Inhibition of lipopolysaccharide-stimulated TNF- promoter activity by S-adenosylmethionine and 5‘-methylthioadenosine. Am J Physiol Gastrointest Liver Physiol, Aug 2004; 287: 352 - 362.
Kupffer cells
- Chin K. Sung, Hongyun She, Shigang Xiong, and Hidekazu Tsukamoto Tumor necrosis factor- inhibits peroxisome proliferator-activated receptor activity at a posttranslational level in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol, May 2004; 286: 722 - 729.
Hepatic stellate cells
- Lingfang Zeng, Hailing Liao, Yi Liu, Tzong-Shyuan Lee, Minjia Zhu, Xian Wang, Michael B. Stemerman, Yi Zhu, and John Y-J ShyySREBP2 downregulates ABCA1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism. J. Biol. Chem., Sep 2004; 10.1074/jbc.M407817200.
HUVECs (Human umbilical vein endothelial cells)
- Radu V. Stan, Eugene Tkachenko, and Ingrid R. Niesman (2004) PV1 Is a Key Structural Component for the Formation of the Stomatal and Fenestral Diaphragms Mol. Biol. Cell published online May 21, 2004, 10.1091/mbc.E03-08-0593
HUVECs (Human umbilical vein endothelial cells), HEK-293, Cos-7 , Hela
- Young-Ho Lee, Scott A. Coonrod, W. Lee Kraus, Mary Anne Jelinek, and Michael R. Stallcup (2005) Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination PNAS, Mar 2005; 102: 3611 - 3616.
- Betty C. Villafuerte and Elizabeth N. Kaytor (2005) An insulin-response element binding protein that ameliorates hyperglycemia in diabetes. J. Biol. Chem., Mar 2005; 10.1074/jbc.M410817200.
L6-myocytes
- Harald Wodrich, Tinglu Guan, Gino Cingolani, Dan Von Seggern, Glen Nemerow, and Larry Gerace (2003) Switch from capsid protein import to adenovirus assembly by cleavage of nuclear transport signals EMBO J., Dec 2003; 22: 6245 - 6255.
NRK cells, Cos-7
- Nigel Carter, Tetsuya Nakamoto, Hisamaru Hirai, Tony Hunter (2002) Nature Cell Biology4, 565 - 573 (mouse embryo fibroblasts).
Mouse embryo fibroblasts
- Bangalore R. Shivakumar, Zoufei Wang, Timothy G. Hammond, and Raymond C. Harris EP24.15 interacts with the angiotensin II type I receptor and bradykinin B(2) receptor. Cell Biochem Funct, Sep 2004;
Porcine kidney epithelial cell line
- Eric. T. Shinohara, Dennis Hallahan and Bo Lu (2004) The Use of Antisense Oligonucleotides in Evaluating Survivin as a Therapeutic Target for Radiation Sensitization in Lung Cancer. Biol. Proced. Online 2004;6:250-256
HUVECs (Human umbilical vein endothelial cells)
- Lin Ma, Nikolas G. Tsatsos, and Howard C. Towle (2005) Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes. J. Biol.Chem., Mar 2005; 280: 12019 - 12027.
Hepatocyte (rat)
- Hubschmann MV, Skladchikova G, Bock E, Berezin V (2005) Neural cell adhesion molecule function is regulated by metalloproteinase-mediated ectodomain release. J Neurosci Res. 2005 Jun 15;80(6):826-37.
L-cells
- Robert F. Schwabe and Hiroaki Sakurai(2005) IKK? phosphorylates, p65 at S468 in transactivaton domain 2, FASEB J, 10.1096/fj.05-3736fje.
MEF transfection
- Harinivas H. Krishnan, Neelam Sharma-Walia, Ling Zeng, Shou-Jiang, Gao, and Bala Chandran(2005) Envelope Glycoprotein gB of Kaposi's Sarcoma-Associated Herpesvirus Is Essential for Egress from Infected Cells, J. Virol., 79: 10952 - 10967
HEK-293 cells
- Liguo Wu, Corina M. Borza, and Lindsey M. Hutt-Fletcher(2005), Mutations of Epstein-Barr Virus gH That Are Differentially Able To Support Fusion with B Cells or Epithelial CellsJ. Virol., Sep 2005; 79: 10923 – 10930 CHO cells and AGS cells
- Weihan Zhao, Tung-Ling L. Chen, Barbara M. Vertel, and Karen J. Colley (2006) The CMP-sialic Acid Transporter Is Localized in the Medial-Trans Golgi and Possesses Two Specific Endoplasmic Reticulum Export Motifs in Its Carboxyl-terminal Cytoplasmic Tail J. Biol. Chem., 281: 31106 - 31118.
HeLa cells
- Catherine K. Yang, Jeong Hoon Kim, and Michael R. Stallcup Mol. Endocrinol. (2006) Role of the N-Terminal Activation Domain of the Coiled-Coil Coactivator in Mediating Transcriptional Activation by ß-Catenin; 20: 3251 - 3262.
Cos-7 cells , Targefect F-2
- Mirianas Chachisvilis, Yan-Liang Zhang, and John A. Frangos (2006) G protein-coupled receptors sense fluid shear stress in endothelial cells. PNAS, Oct 2006; 103: 15463 - 15468.
Bovine aortic endothelial cells , targefect F-2 plus virofect
- Young-Ho Lee and Michael R. Stallcup. (2006) Interplay of Fli-I and FLAP1 for regulation of ß-catenin dependent transcription. Nucleic Acids Res.; 34: 5052 - 5059.
HEK-293 cells transfected with Targefect F1
- Tian-Fang Li, Di Chen, Qiuqian Wu, Mo Chen, Tzong-jen Sheu, Edward M. Schwarz, Hicham Drissi, Michael Zuscik, and Regis J. O'Keefe. (2006) Transforming Growth Factor-beta Stimulates Cyclin D1 Expression through Activation of beta-Catenin Signaling in Chondrocytes. J. Biol. Chem., Jul 2006; 281: 21296 - 21304. Primary chondrocytes
- Smarajit Bandyopadhyay, Mohammad Z. Ashraf, Pamela Daher, Philip H. Howe, and Paul E. DiCorleto (2007) HOXA9 Participates in the Transcriptional Activation of E-Selectin in Endothelial Cells Mol. Cell. Biol; 27: 4207 - 4216.
Human umbilical vein endothelial cells (HUVECs)
- Nancy Gertzberg, Tina Gurnani, Paul Neumann, Anne-Kay Forbes, Natacha Jean-Louis, and Arnold Johnson. (2007) Tumor necrosis factor-{alpha} causes barrier dysfunction mediated by tyrosine198 and tyrosine218 in beta-actin. Am J Physiol Lung Cell Mol Physiol, 293: L1219 - L1229.
Bovine pulmonary microvascular endothelial cells, 79% transfection efficiency using F-2 plus virofect
- Mélanie Laramée, Catherine Chabot, Monikca Cloutier, Raphaëlle Stenne, Marina Holgado-Madruga, Albert J. Wong, and Isabelle Royal (2007) The Scaffolding Adapter Gab1 Mediates Vascular Endothelial Growth Factor Signaling and Is Required for Endothelial Cell Migration and Capillary Formation. J. Biol. Chem., Mar 2007; 282: 7758 - 7769.
Endothelial cells (Targefect siRNA kit)
- Xiaomei Qin, Jianwei Tian, Peng Zhang, Yanbo Fan, Li Chen, Youfei Guan, Yi Fu, Yi Zhu, Shu Chien, and Nanping Wang. (2007) Laminar shear stress up-regulates the expression of stearoyl-CoA desaturase-1 in vascular endothelial cells. Cardiovasc Res, Jun 2007; 74: 506 - 514.
Human umbilical vein endothelial cells (HUVECs)
- Li-Wu Qian, Jianping Xie, Fengchun Ye, and Shou-Jiang Gao (2007) Kaposi‘s Sarcoma-Associated Herpesvirus Infection Promotes Invasion of Primary Human Umbilical Vein Endothelial Cells by Inducing Matrix Metalloproteinases. J. Virol., Jul 2007; 81: 7001 - 7010.
Transfection of bacterial artifical chromosomes (BACs) into HUVECs using Targefect-HUVEC
- Huan Lou and Neil Kaplowitz (2007) Glutathione Depletion Down-regulates Tumor Necrosis Factor {alpha}-induced NF-{kappa}B Activity via I{kappa}B Kinase-dependent and -independent Mechanisms. J. Biol. Chem., Oct 2007; 282: 29470 - 29481.
Primary Mouse Hepatocytes, Targefect F-1
- David Y. Lee, Irina Ianculescu, Daniel Purcell, Xing Zhang, Xiaodong Cheng, and Michael R. Stallcup (2007) Surface-Scanning Mutational Analysis of Protein Arginine Methyltransferase 1: Roles of Specific Amino Acids in Methyltransferase Substrate Specificity, Oligomerization, and Coactivator Function. Mol. Endocrinol; 21: 1381 - 1393.
CV-1 cells
- Corttrell M. Kinney, Unni M. Chandrasekharan, Lori Mavrakis, and Paul E. DiCorleto (2008) VEGF and thrombin induce MKP-1 through distinct signaling pathways: role for MKP-1 in endothelial cell migration. Am J Physiol Cell Physiol, Jan 2008; 294: C241 - C250.
Human umbilical vein endothelial cells (HUVECs)
- Ying Jing, Niladri Mal, P. Stephen Williams, Maritza Mayorga, Marc S. Penn, Jeffrey J. Chalmers, and Maciej Zborowski (2008) Quantitative intracellular magnetic nanoparticle uptake measured by live cell magnetophoresis. FASEB J; 22: 4239 - 4247.
- Julie Ann Mayer, John Foley, Damon De La Cruz, Cheng-Ming Chuong, and Randall Widelitz (2008) Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface. Am. J. Pathol., Nov 2008; 173: 1339 - 1348.
Primary keratinocytes- Targefect F-1 (would benefit by using Virofect)
- David E. Nowak, Bing Tian, Mohammad Jamaluddin, Istvan Boldogh, Leoncio A. Vergara, Sanjeev Choudhary, and Allan R. Brasier. (2008) RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF-{kappa}B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes. Mol. Cell. Biol; 28: 3623 - 3638.
Murine embryo fibroblasts transfected with Targefect- MEF
- Maud Martin, Michael Potente, Veerle Janssens, Didier Vertommen, Jean-Claude Twizere, Mark H. Rider, Jozef Goris, Stefanie Dimmeler, Richard Kettmann, and Franck Dequiedt (2008) Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis. PNAS, Mar 2008; 105: 4727 - 4732.
Human umbilical vein endothelial cells (HUVECs) transfected with Targefect F-2 plus Virofect
- Larry Pederson, Ming Ruan, Jennifer J. Westendorf, Sundeep Khosla, and Merry Jo Oursler (2008) Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate. PNAS; 105: 20764 - 20769.
Human mesenchymal stem cells . Targefect-Osteoblast (Tarefect F-2 plus virofect)
- Jason H. Cheng, Hongyun She, Yuan-Ping Han, Jiaohong Wang, Shigang Xiong, Kinji Asahina, and Hidekazu Tsukamoto. (2008) Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis. Am J Physiol Gastrointest Liver Physiol, Jan 2008; 294: G39 - G49.
Hepatic stellate cells
- Arnold Johnson (2009) TNF-induced activation of pulmonary microvessel endothelial cells: a role for GSK3ß. Am J Physiol Lung Cell Mol Physiol; 296: L700 - L709.
Microvascular endothelial cells
- Chen-Yin Ou, Jeong Hoon Kim, Catherine K. Yang, and Michael R. Stallcup (2009) Requirement of Cell Cycle and Apoptosis Regulator 1 for Target Gene Activation by Wnt and ß-Catenin and for Anchorage-independent Growth of Human Colon Carcinoma Cells J. Biol. Chem., Jul 2009; 284: 20629 - 20637.
Human colon carcinoma cells
- Yan-Liang Zhang, John A. Frangos, and Mirianas Chachisvilis (2009). Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells. Am J Physiol Cell Physiol, 296: C1391 - C1399.
MC3T3-E1
- Cortrell M. Kinney, Unni M. Chandrasekharan, Lin Yang, Jianzhong Shen, Michael Kinter, Michael S. McDermott, and Paul E. DiCorleto (2009) Histone H3 as a novel substrate for MAP kinase phosphatase-1Corttrell Am J Physiol Cell Physiol, Feb 2009; 296: C242 - C249.
Cos-1 cells (Targefect F-2 plus peptide enhancer)
- Indira Padmalayam, Sumera Hasham, Uday Saxena, and Sivaram Pillarisetti (2009) Lipoic Acid Synthase (LASY): A Novel Role in Inflammation, Mitochondrial Function, and Insulin Resistance Diabetes, Mar 2009; 58: 600 - 608.
Human skeletal muscle myoblasts, Human microvascular endothelial cells (HMVECs)
- Fuchun Zhou, Qiuhua Li, and Shou-Jiang Gao. (2009) A sequence-independent in vitro transposon-based strategy for efficient cloning of genomes of large DNA viruses as bacterial artificial chromosomes Nucleic Acids Res., Jan 2009; 37: e2.
Transfection of bacterial artificial chromosomes (BAC) DNA into NIH-3T3 cells with Targefect-293 (F-2- a component of Targefect-BAC kit)
- Mohini A. Patil, Susie A. Lee, Everardo Macias, Ernest T. Lam, Chuanrui Xu, Kirk D. Jones, Coral Ho, Marcelo Rodriguez-Puebla, and Xin Chen. (2009) Role of Cyclin D1 as a Mediator of c-Met– and ß-Catenin–Induced Hepatocarcinogenesis. Cancer Res., Jan 2009; 69: 253 - 261.
Primary hepatocytes
- Catherine Chabot, Kathleen Spring, Jean-Philippe Gratton, Mounib Elchebly, and Isabelle Royal (2009) New Role for the Protein Tyrosine Phosphatase DEP-1 in Akt Activation and Endothelial Cell Survival Mol. Cell. Biol., Jan 2009; 29: 241 - 253.
HUVECs
- Tsubasa Sakai, Masato Aoyama, Takehiro Kusakabe, Motoyuki Tsuda, and Honoo Satake. (2010) Functional Diversity of Signaling Pathways through G Protein–Coupled Receptor Heterodimerization with a Species-Specific Orphan Receptor Subtype Mol. Biol. Evol., 27: 1097 - 1106.
HEK-293 cells
- Payal Khanna, Tara Yunkunis, Hari S. Muddana, Hsin Hsin Peng, Avery August, and Cheng Dong (2010) p38 MAP kinase is necessary for melanoma-mediated regulation of VE-cadherin disassembly Am J Physiol Cell Physiol, 298: C1140 - C1150.
HUVECa
- Chuan-Rui Xu, Susie Lee, Coral Ho, Prashant Bommi, Shi-Ang Huang, Siu Tim Cheung, Goberdhan P. Dimri, and Xin Chen (2009) Bmi1 Functions as an Oncogene Independent of Ink4A/Arf Repression in Hepatic Carcinogenesis Mol. Cancer Res., 7: 1937 - 1945.
Human hepatocellular carcinoma cells (Targefect-hepatocyte)
- Weifei Zhu, Unni M. Chandrasekharan, Smarajit Bandyopadhyay, Sidney M. Morris, Jr., Paul E. DiCorleto, and Vikram S. Kashyap (2010)Thrombin induces endothelial arginase through AP-1 activation Am J Physiol Cell Physiol, 298: C952 - C960.
Rat aortic endothelial cells
- Bon-Hun Koo, David M. Coe, Laura J. Dixon, Robert P.T. Somerville, Courtney M. Nelson, Lauren W. Wang, Mary Elizabeth Young, Daniel J. Lindner, and Suneel S. Apte (2010) ADAMTS9 Is a Cell-Autonomously Acting, Anti-Angiogenic Metalloprotease Expressed by Microvascular Endothelial Cells Am. J. Pathol., 176: 1494 - 1504.
Human Microvacular Endothelial Cells, HUVECs
- Sylwia Owczarek, Darya Kiryushko, Marianne Hald Larsen, Jette Sandholm Kastrup, Michael Gajhede, Carmen Sandi, Vladimir Berezin, Elisabeth Bock, and Vladislav Soroka (2010) Neuroplastin-55 binds to and signals through the fibroblast growth factor receptor FASEB J, Apr 2010; 24: 1139 - 1150.
293 cells
References citing luciferase reporter products from Targeting Systems
- Jinming Yang, Snjezana Zaja-Milatovic, Yee-Mon Thu, Francis Lee, Richard Smykla, and Ann Richmond (2009) Molecular determinants of melanoma malignancy: selecting targets for improved efficacy of chemotherapy. Mol. Cancer Ther., Mar 2009; 8: 636 - 647.
- Tannous BA (2009) Gaussia luciferase reporter assay for monitoring biological processes in culture and in vivo. Nature Protocols 4, - 582 - 591 (2009)
- Wurdinger T, Badr C and Tannous B (2008) Gaussia luciferase blood level as an index of cell growth and proliferation
- Wurdinger T, Badr C, Pike L, de Kline R, Weissleder R, Breakerfield X, and Tannous B (2008) A secreted luciferase for ex vivo monitoring of in vivo processes. Nature Methods - 5, 171 - 173
- Cheng G and Davis RE (2007). An improved and secreted luciferase reporter for schistosomes. Molecular & Biochemical Parasitology 155 (2007) 167–171.
- Drug Discovery Today: Technologies Volume 1, Issue 4, December 2004, Pages 357-364
- Nicola Ternette,1 Daniela Stefanou,1 Seraphin Kuate,1 Klaus Überla,1 and Thomas Grunwald (2007) Expression of RNA virus proteins by RNA polymerase II dependent expression plasmids is hindered at multiple steps. Virol J. 2007; 4: 51.
- Guofeng Chenga,1, Leah Cohenb,1, Claudette Mikhli b, Marzena Jankowska-Anyszka c (2007) In vivo translation and stability of trans-spliced mRNAs in nematode embryos.
Relevant interesting papers on new applications of Gaussia luciferase
- Development of a Dual-Luciferase Reporter System for In Vivo Visualization of MicroRNA Biogenesis and Posttranscriptional RegulationJi Young Lee, Soonhag Kim, Do Won Hwang, Jae Min Jeong, June-Key Chung, Myung Chul Lee, and Dong Soo Lee
J. Nucl. Med., Feb 2008; 49: 285 - 294.
- Sensitive In Vivo Detection of Primary T Cells Expressing Membrane-Anchored Gaussia Luciferase for the Study of Adoptive T Cell Immunotherapy in Murine Models of Malignancy.
- Renier J. Brentjens, Elmer Santos, Raymond Yeh, Krista La Perle, Ricardo Toledo-Crow, Yan Nikhamin, Blesida Punzalan, David Entenberg, Iana Aranda, Bleserene Punzalan, Steven Larson, and Michel Sadelain Blood (ASH Annual Meeting Abstracts), Nov 2006; 108: 3685
References citing red and green-emitting luciferases from the Italian firefly Luciola Italica
Note : The red- and green-emitting Luciola luciferases are improved significantly brighter versions (mammalian expression) of the luciferases mentioned in the references below
- “A Redshifted Codon-Optimized Firefly Luciferase is a Sensitive Reporter for Bioluminescence Imaging,“ H. Caysa, R. Jacob, N. Müther, B. Branchini, M. Messerle and A. Söling, Photochemical and Photobiological Sciences, 8: 52-56 (2009).
- “Spectral-Resolved Gene Technology for Multiplexed Bioluminescence and High-Content Screening,“ E. Michelini, L. Cevenini, L. Mezzanotte, D. Ablamsky, T. Southworth, B. Branchini and A. Roda, Analytical Chemistry 80: 260-267 (2008).
- “Combining Intracellular and secreted bioluminescent reporter proteins for multicolor cell-based assays,“ E. Michelini, L. Cevenini, L. Mezzanotte, D. Ablamsky, T. Southworth, B. R. Branchini and A. Roda, Photochem Photobiol Sci. 7: 212-217 (2008).
- “Development of a Multiplexed Bioluminescent Cell-based Assay wit the Luc Gene from Luciola italica for High Throughput Screening of Cholesterol-Lowering Drugs.“ E. Michelini, T. L. Southworth, D. Ablamsky, B. R. Branchini and A. Roda, in Proceedings of the 14th International Symposium on Bioluminescence and Chemiluminescence: Chemistry Biology and Applications, San Diego, CA, October 15-19, 2006, edited by A. A. Szalay, P. J. Hill, L. J. Kricka and P. E. Stanley, World Scientific Publishing Co. Pte. Ltd., Singapore, pp. 119-122, 2007.
- A redshifted codon-optimized firefly luciferase is a sensitive reporter for bioluminescence imaging Henrike Caysa, Roland Jacob, Nadine Müther, Bruce Branchini, Martin Messerle and Ariane Söling, Photochem. Photobiol. Sci., 2009, 8, 52
- Improved red-emitting firefly luciferase for biotechnical applications. Audrey Davis, Connecticut College, 2009 . Can be accessed at the following link. digitalcommons.conncoll.edu/chemhp/5/
- “Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications,“ B.R. Branchini, D.M. Ablamsky, M.H. Murtiashaw, L. Uzasci*, H. Fraga and T.L. Southworth, Analytical Biochemistry, 361 (2): 253-262 (2007).
- “uciferase from the Italian firefly Luciola italica: Molecular cloning and expression,“ B.R. Branchini, T.L. Southworth, J.P. DeAngelis*, A. Roda, and E. Michelini, in Comparative Biochemistry and Physiology, Part B, 145, pp.159-167 (2006).
- “NMR Assignment of the Backbone Resonances of the Firefly Luciferase C-Terminal 14.3 kDa Domain,“ B.R. Branchini, S.A. Gonzales, and R. Magyar in Journal of Biomolecular NMR, vol 33, p. 73 (2005).
- “Red- and Green-Emitting Firefly Lucifease Mutants for Bioluminescent Reporter Applications,“ B.R. Branchini, T.L. Southworth, N.K. Khattak*, E. Michelini, and A. Roda in Analytical Biochemistry, vol. 345, pp.140-148 (2005).
Some relevant interesting papers
- Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer Brian A. Rabinovich, Yang Ye, Tamara Etto, Jie Qing Chen, Hyam I. Levitsky, Willem W. Overwijk, Laurence J. N. Cooper, Juri Gelovani, and Patrick Hwu PNAS, Sep 2008; 105: 14342 - 14346.
- “Synergistic Mutations Produce Blue-Shifted Bioluminescence in Firefly Luciferase,“ B. R. Branchini, D. M. Ablamsky, J. M. Rosenman*, L. Uzasci*, T. L. Southworth and M. Zimmer, Biochemistry 46 (48): 13847-13855 (2007).
Citations describing Vargula/ (Cypridina luciferase)
- Thompson, E. M., Nagata, S., and Tsuji, F. I. (1989) Cloning and expression of the cDNA from the ostracod vargula hilgendorfi Proc. Natl. Acad. Sci. U. S. A. 86, 6567–6571
- Thompson, E. M., Nagata, S., and Tsuji, F. I. (1990) Vargula hilgendorfii luciferase: a secreted reporter enzyme for monitoring gene expression in mammalian cells Gene (Amst.) 96, 257–262
- Shin-ya Nishide, Sato Honma, Yoshihiro Nakajima, Masaaki Ikeda, Kenkichi Baba, Yoshihiro Ohmiya, and Ken-ichi Honma (2006) New reporter system for Per1 and Bmal1 expressions revealed self-sustained circadian rhythms in peripheral tissues. Genes Cells, Oct 2006; 11: 1173 - 1182.
- S Inouye, Y Ohmiya, Y Toya, and FI Tsuji (1992) Imaging of Luciferase Secretion from Transformed Chinese Hamster Ovary Cells PNAS, Oct 1992; 89: 9584 - 9587. (this paper shows that vargula luciferase can be used to image single cells . Also shows the chemistry of the luciferase reaction conc of luciferin used for assay was 43 nM (o.043 uM) in tris HCL pH 7. Adherent CHO cells,
Targefect siRNA references (Gene Silencing)
- Boris A Hesser, Xiao Huan Liang, Gieri Camenisch, Suya Yang, David Lewin, Richard Scheller, Napoleone Ferrara, and Hans-Peter Gerber (2004) Down syndrome critical region protein1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells. Blood, 10.1182/blood-2004-01-0273.(HDMVECs) Human Dermal microvascular endothelial cells
- Partovian C, Simons M (2004) Regulation of protein kinase B/Akt activity and Ser(473) phosphorylation by protein kinase Calpha in endothelial cells.Cell Signal. 2004 Aug;16(8):951-7.
- Radu V. Stan, Eugene Tkachenko, and Ingrid R. Niesman (2004) PV1 Is a Key Structural Component for the Formation of the Stomatal and Fenestral DiaphragmsMol. Biol. Cell published online May 21, 2004, 10.1091/mbc.E03-08-0593 HUVECs (Human umbilical vein endothelial cells), HEK-293, Cos-7 , Hela
- Radu V. Stan. Multiple PV1 dimers reside in the same stomatal or fenestral diaphragmAm J Physiol Heart Circ Physiol, Apr 2004; 286: 1347 - 1353.
- Jiaping Wu, Cherie Parungo, Guifu Wu, Peter M. Kang, Roger J. Laham, Frank W. Sellke, Michael Simons, and Jian Li (2004) PR39 Inhibits Apoptosis in Hypoxic Endothelial Cells: Role of Inhibitor Apoptosis Protein-2. Circulation, 109: 1660 - 1667. BAECs (Bovine aortic endothelial cells)
- Raquel Pluvinet, Jordi Petriz, Joan Torras, Inmaculada Herrero-Fresneda, Josep M Cruzado, Josep M Grinyo, and Josep M Aran. RNAi-mediated silencing of CD40 prevents leukocyte adhesion on CD154-activated endothelial cells. Blood, Aug 2004; 10.1182/blood-2004-03-0817. HUVECs
- Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky, Marc Montminy PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine10, 530 - 534 (01 May 2004) LettersHepatocytes
- Jeong Hoon Kim, Hongwei Li, and Michael R. Stallcup (2003) CoCoA, a Nuclear Receptor Coactivator which Acts through an N-Terminal Activation Domain of p160 CoactivatorsMolecular Cell 2003 12: 1537-1549 MCF-7, COS-7
- C. Radel and V. Rizzo. Integrin mechanotransduction stimulates caveolin-1 phosphorylation and recruitment of Csk to mediate actin reorganization. Am J Physiol Heart Circ Physiol, Feb 2005; 288: 936 - 945. Bovine aortic endothelial cells (BAECs)
- Sanjeev Choudhary, Tianlin Xiao, Leoncio A. Vergara, Sanjay Srivastava, David Nees, Joram Piatigorsky, and Naseem H. Ansari. Role of Aldehyde Dehydrogenase Isozymes in the Defense of Rat Lens and Human Lens Epithelial Cells against Oxidative Stress. Invest. Ophthalmol. Vis. Sci., Jan 2005; 46: 259 - 267. HLECs (Human Lens Epithelial Cells) , rat and mouse lenses
- Yang Luo and Glenn L. Radice (2005) N-cadherin acts upstream of VE-cadherin in controlling vascular morphogenesis. J. Cell Biol., Apr 2005; 169: 29 - 34. HUVEC, HDMVEC,
- Tomoaki Murakami, Hitoshi Takagi, Kiyoshi Suzuma, Izumi Suzuma, Hirokazu Ohashi, Daisuke Watanabe, Tomonari Ojima, Eri Suganami, Masafumi Kurimoto, Hideaki Kaneto, Yoshihito Honda, and Nagahisa Yoshimura(2005) Angiopoietin-1 Attenuates H2O2-induced SEK1/JNK Phosphorylation through the Phosphatidylinositol 3-Kinase/Akt Pathway in Vascular Endothelial Cells, J. Biol. Chem., Sep 2005; 280: 31841 - 31849.
- Chohreh Partovian, Zhenwu Zhuang, Karen Moodie, Michelle Lin, Noriyuki Ouchi, William C. Sessa, Kenneth Walsh, and Michael Simons(2005)PKC Activates eNOS and Increases Arterial Blood Flow In Vivo Circ. Res., 97: 482 - 487
- Corttrell M. Kinney, Unni M. Chandrasekharan, Lori Mavrakis, and Paul E. DiCorleto 92008) VEGF and thrombin induce MKP-1 through distinct signaling pathways: role for MKP-1 in endothelial cell migration
Am J Physiol Cell Physiol, 294: C241 - C250.
- Arnold Johnson (2009) TNF-induced activation of pulmonary microvessel endothelial cells: a role for GSK3ß. Am J Physiol Lung Cell Mol Physiol, Apr 2009; 296: L700 - L709.
- Catherine K. Yang, Jeong Hoon Kim, Hongwei Li, and Michael R. Stallcup (2006) Differential Use of Functional Domains by Coiled-coil Coactivator in Its Synergistic Coactivator Function with -Catenin or GRIP1. J. Biol. Chem., Feb 2006; 281: 3389 - 3397.
- Smarajit Bandyopadhyay, Mohammad Z. Ashraf, Pamela Daher, Philip H. Howe, and Paul E. DiCorleto (2007) HOXA9 Participates in the Transcriptional Activation of E-Selectin in Endothelial Cells
Mol. Cell. Biol., 27: 4207 - 4216
- Corttrell M. Kinney, Unni M. Chandrasekharan, Lin Yang, Jianzhong Shen, Michael Kinter, Michael S. McDermott, and Paul E. DiCorleto (2009) Histone H3 as a novel substrate for MAP kinase phosphatase-1 Am J Physiol Cell Physiol, Feb 2009; 296: C242 - C249
- David E. Nowak, Bing Tian, Mohammad Jamaluddin, Istvan Boldogh, Leoncio A. Vergara, Sanjeev Choudhary, and Allan R. Brasier (2008) RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF-B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes
Mol. Cell. Biol., 28: 3623 - 3638.
- Mélanie Laramée, Catherine Chabot, Monikca Cloutier, Raphaëlle Stenne, Marina Holgado-Madruga, Albert J. Wong, and Isabelle Royal (2007) The Scaffolding Adapter Gab1 Mediates Vascular Endothelial Growth Factor Signaling and Is Required for Endothelial Cell Migration and Capillary Formation
J. Biol. Chem., Mar 2007; 282: 7758 - 7769.
- Payal Khanna, Tara Yunkunis, Hari S. Muddana, Hsin Hsin Peng, Avery August, and Cheng Dong (2010) p38 MAP kinase is necessary for melanoma-mediated regulation of VE-cadherin disassembly
Am J Physiol Cell Physiol, 298: C1140 - C1150.
- David Y. Lee, Jeffrey P. Northrop, Min-Hao Kuo, and Michael R. Stallcup 92006) Histone H3 Lysine 9 Methyltransferase G9a Is a Transcriptional Coactivator for Nuclear Receptors
J. Biol. Chem., 281: 8476 - 8485.
- Bon-Hun Koo, David M. Coe, Laura J. Dixon, Robert P.T. Somerville, Courtney M. Nelson, Lauren W. Wang, Mary Elizabeth Young, Daniel J. Lindner, and Suneel S.(2010) Apte ADAMTS9 Is a Cell-Autonomously Acting, Anti-Angiogenic Metalloprotease Expressed by Microvascular Endothelial Cells
Am. J. Pathol., Mar 2010; 176: 1494 - 1504.
- Weifei Zhu, Unni M. Chandrasekharan, Smarajit Bandyopadhyay, Sidney M. Morris, Jr., Paul E. DiCorleto, and Vikram S. Kashyap (2010) Thrombin induces endothelial arginase through AP-1 activation
Am J Physiol Cell Physiol, 298: C952 - C960.
- Indira Padmalayam, Sumera Hasham, Uday Saxena, and Sivaram Pillarisetti (2009) Lipoic Acid Synthase (LASY): A Novel Role in Inflammation, Mitochondrial Function, and Insulin Resistance
Diabetes, 58: 600 - 608.
- Maud Martin, Michael Potente, Veerle Janssens, Didier Vertommen, Jean-Claude Twizere, Mark H. Rider, Jozef Goris, Stefanie Dimmeler, Richard Kettmann, and Franck Dequiedt (2008) Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis
PNAS, Mar 2008; 105: 4727 - 4732.
- Nancy Gertzberg, Tina Gurnani, Paul Neumann, Anne-Kay Forbes, Natacha Jean-Louis, and Arnold Johnson (2007) Tumor necrosis factor- causes barrier dysfunction mediated by tyrosine198 and tyrosine218 in -actin
Am J Physiol Lung Cell Mol Physiol, Nov 2007; 293: L1219 - L1229.
- Catherine Chabot, Kathleen Spring, Jean-Philippe Gratton, Mounib Elchebly, and Isabelle Royal (2009) New Role for the Protein Tyrosine Phosphatase DEP-1 in Akt Activation and Endothelial Cell Survival
Mol. Cell. Biol., 29: 241 - 253.
- Young-Ho Lee and Michael R. Stallcup (2006) Interplay of Fli-I and FLAP1 for regulation of ß-catenin dependent transcription
Nucleic Acids Res., 34: 5052 - 5059.
- Mohini A. Patil, Susie A. Lee, Everardo Macias, Ernest T. Lam, Chuanrui Xu, Kirk D. Jones, Coral Ho, Marcelo Rodriguez-Puebla, and Xin Chen (2009)Role of Cyclin D1 as a Mediator of c-Met– and ß-Catenin–Induced Hepatocarcinogenesis
Cancer Res., Jan 2009; 69: 253 - 261.
- Beiyun Zhou, David K. Ann, Xian Li, Kwang-Jin Kim, Helen Lin, Parviz Minoo, Edward D. Crandall, and Zea Borok (2007) Hypertonic induction of aquaporin-5: novel role of hypoxia-inducible factor-1{alpha}. Am J Physiol Cell Physiol, Apr 2007; 292: C1280 - C1290.
MLE-15 Mouse Lung epithelial cells, transfection of siRNA using Targefect-siRNA kit
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